How long does verapamil take to work for migraines? Verapamil is commonly used for blood pressure and heart conditions. It takes at least four to six weeks for it to become effective in treating migraine. Side effects such as ankle swelling, constipation, and fatigue are common.
Is verapamil good for migraine headaches? Calcium channel blockers have demonstrated efficacy in investigative use for prophylaxis of migraine and cluster headaches. In particular, verapamil, with its low side-effect profile, appears to be a promising alternative to the currently available agents for prophylactic treatment of chronic recurring headaches.
Why is verapamil used for migraines? How It Works. Like all calcium channel blockers, verapamil allows smooth muscles to relax by preventing calcium from entering smooth muscle cells. Large blood vessels have smooth muscles in their walls, so smooth muscle relaxation prevents these blood vessels from constricting (narrowing).
What is the most prescribed drug for migraines? The most commonly prescribed class of drugs for migraine are the triptans. These are all meant to be taken on an as-needed basis, at the first sign of headache, and they include Sumatriptan (Imitrex); Zolmitriptan (Zomig); Rizatriptan (Maxalt); and Eletriptan (Relpax).