Why are steroids given for migraines? What is the hypothesized mechanism behind dexamethasone and migraine prevention? One of the presumed causes of migraines is a state of neurogenic inflammation (3). Corticosteroids such as dexamethasone could mitigate this inflammatory response, thereby decreasing pain and recurrence of migraines.
How fast do steroids work for migraines? Eighty-five percent of the patients experienced a reduction in headache frequency and no patients presented severe attacks during the first 6 days. With regard to the following 10 days, 46% of the patients experienced at least 2 days without headache and 58% less intense attacks.
How often can you take steroids for migraines? The usual dose is 8 mg daily for two days. Other doctors prescribe a six-day course of methylprednisolone (Medrol Dosepak).
How much prednisone should I take for migraines? Either prednisone 60 mg to 80 mg or dexamethasone should be used. A Medrol dose pack does not provide a high enough dose or a long enough duration to be of benefit.