Do they still make Midrin for migraines? Midrin, Nodolor (isometheptene / dichloralphenazone / acetaminophen) Midrin is a combination medication containing isometheptene, dichloralphenazone, and acetaminophen that’s used to treat migraines and headaches, but it’s no longer available in the U.S. because it was discontinued.
What has replaced Midrin? Prodrin is a similar medication that is still available. It contains two of the three ingredients that were in Midrin, plus caffeine: acetaminophen, 325 mg: an analgesic.
Why did they take Midrin off the market? Midrin was discontinued by Caraco Pharmaceuticals as of 2009, after an FDA seizure of 33 drugs manufactured by Caraco Pharmaceuticals due to cGMP (Current Good Manufacturing Practices) violations. Generic forms of Amidrine were also discontinued due to loss of FDA grandfather approval status.
Is generic Midrin still available? Neither the brand-name Midrin nor any generic equivalents are currently manufactured. In 2017, the Food and Drug Administration (FDA) notified manufacturers and labelers to stop distributing drug products that contain isometheptene mucate, one of the active ingredients found in Midrin.