Can trazodone trigger migraine? To our knowledge, there are few reports of severe headache as an adverse effect linked to trazodone use. In 1992, Workman et al. reported that a 35-year-old patient who possessed a genetic predisposition toward migraine suffered from severe migraine headache after trazodone treatment.
What is the most prescribed drug for migraines? The most commonly prescribed class of drugs for migraine are the triptans. These are all meant to be taken on an as-needed basis, at the first sign of headache, and they include Sumatriptan (Imitrex); Zolmitriptan (Zomig); Rizatriptan (Maxalt); and Eletriptan (Relpax).
Which antidepressant is best for migraines? Amitriptyline is the best-studied and most common antidepressant used for migraine prevention. It has a long history of use for migraine. For some people, amitriptyline may work well but cause intolerable side effects. In this case, nortriptyline may be an alternative.
What medication is used for migraines and anxiety? Amitriptiline can be used both in mood disorders and migraine prevention. Flunarizine and beta-blockers may help if anxiety is present. Pregabalin has demonstrated efficacy in anxiety disorders and fibromyalgia.