Can steroids cause migraines? Prednisone in itself can cause migraine attacks if excessive amounts have been taken over a long period of time. Prolonged steroid therapy can produce significant side effects and strict medical supervision is important.
How do steroids help migraines? What is the hypothesized mechanism behind dexamethasone and migraine prevention? One of the presumed causes of migraines is a state of neurogenic inflammation (3). Corticosteroids such as dexamethasone could mitigate this inflammatory response, thereby decreasing pain and recurrence of migraines.
How long does it take for prednisone to work for migraines? Eighty-five percent of the patients experienced a reduction in headache frequency and no patients presented severe attacks during the first 6 days. With regard to the following 10 days, 46% of the patients experienced at least 2 days without headache and 58% less intense attacks.
What can I take for a migraine while on prednisone? Acetaminophen is recommended for headaches when taking prednisone.