What is the most effective triptan for migraine? A 2019 study compared the effectiveness and dosage form of seven triptan medications and found: Among oral medications, eletriptan at a 40-milligram (mg) dose had the highest effectiveness compared with all oral medications. Naratriptan (2.5 mg) had the lowest effectiveness among other oral triptans.
Which triptan has least side effects? Of the triptans reviewed, at clinically relevant doses, almotriptan 12.5 mg, naratriptan 2.5 mg and sumatriptan 50 mg had the lowest incidence of CNS side-effects, while eletriptan 40 and 80 mg, rizatriptan 10 mg and zolmitriptan 2.5 and 5 mg had the highest incidence.
Which triptan works fastest? The maximum dose is 200 mg per 24 hours. Subcutaneous sumatriptan (6 mg) is more effective than oral sumatriptan, but its use is associated with more adverse events . Subcutaneous sumatriptan has the fastest onset of action.
What is the most prescribed drug for migraines? The most commonly prescribed class of drugs for migraine are the triptans. These are all meant to be taken on an as-needed basis, at the first sign of headache, and they include Sumatriptan (Imitrex); Zolmitriptan (Zomig); Rizatriptan (Maxalt); and Eletriptan (Relpax).